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Two dominant genetic anomalies in the Holstein breed discovered through analysis of mortality rates by sire families

Contact : Aurélien Capitan
Reference : Besnard F., Boussaha M., Leclerc H., Grohs C., Jewell N. Pinton A. Barsac H., Jourdain J., Femenia M., Dorso L., Strugnell B., Floyd T., Danchin-Burge C., Guatteo R., Cassart D., Hubin X., Mattalia S., Boichard D., Capitan A. 2022. Detailed analysis of mortality rates in the female progeny of 1001 Holstein bulls allows the discovery of new dominant genetic defects. J Dairy Sci, 106, https://doi.org/10.3168/jds.2022-22365

Origin of cleft palate in Limousin cattle elucidated: involvement of MYH3 gene

Contact : Amandine Duchesne
Reference : Vaiman A., Fritz S., Beauvallet C., Boussaha M., Grohs C., Daniel‑Carlier N., Relun A., Boichard D., Vilotte J.L.,  Duchesne A. 2022. Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle. Genetics Selection Evolution, 54:71. https://doi.org/10.1186/s12711-022-00762-2

Genetics Selection Evolution : Open Access journal in progress

Contact : Helene Hayes et Didier Boichard

Reference : https://gsejournal.biomedcentral.com/

Integration of complex annotations in Bayesian genomic prediction models

Contact : Andrea Rau et Pascal Croiseau 
References :
•    Mollandin, F., Gilbert, H., Croiseau, P., Rau, A. (2022) Accounting for overlapping annotations in genomic prediction models of complex traits. BMC Bioinformatics, 23:65. 
•    Mollandin, F. (2022) Intégration d’annotations fonctionnelles dans des modèles de prédiction génomique bayésiens. Thèse de doctorat en mathématiques appliquées, Université de Paris Saclay.
•    Logiciel BayesRCO: https://github.com/fmollandin/BayesRCO

Genetic indexes for the selection of cheese-making properties in milk

Contact : Marie-Pierre Sanchez 

Reference : Sanchez MP, Tribout T, Fritz S, Wolf V, Laithier C, Brochard M, Boichard D. 2022. Opportunities for genomic selection of cheese-making traits in Montbéliarde cows. J. Dairy Sci. 105, 5206-5220. https://doi.org/10.3168/jds.2021-21558

Single-step genomic evaluation for improved resistance to bovine paratuberculosis

Contact : Marie-Pierre Sanchez 

Reference : Sanchez M.-P., Tribout T., Fritz S., Guatteo R., Fourichon C., Schibler L., Delafosse A., Boichard D. New insights into genetic resistance to paratuberculosis in Holstein via a single-step genomic evaluation. 2022. Genet. Sel. Evol. 54:67. https://doi.org/10.1186/s12711-022-00757-z 

Publication of dairy cattle indexes estimated by the "Single Step" method  

Contact : Thierry Tribout, Didier Boichard

Study of heat tolerance and genetic x temperature interactions in cattle

Contact : Aurélie Vinet

Reference : Vinet A., Mattalia S., Vallée R., Bertrand C., Persyn B., Cuyabano B.C.D., Boichard D. Estimation of genotype by temperature-humidity index interactions on milk production and udder health traits in the Montbeliarde cows. Genet Sel Evol,