Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDE) are persistant organic pollutants present in aquatic environments despite their either total or partial removal from the market. Chronic exposition of zebrafish, a fish model, to a mixture of PCB and PBDE that is representative of European environmental situations, affects the energy metabolism, growth and reproduction in the exposed zebrafish (F0) as well as the behavior of their non-exposed offspring (F1-F4) (Horri et al., 2018 ; Alfonso et al., 2019).
In this press release, discover the studies led by INRAE on COVID-19, studies ranging from virology to sociology, epidemiology, ecology and mathematics.
Whole genome sequencing has changed many fields in genetics: selection, biodiversity, understanding the genotype-phenotype relationship. The idea of a "1000 Genomes" project, tested in cattle, consists of sharing sequence data obtained by different partners to facilitate the extraction of information that answers the different research questions. Here we present how this will be done for the chicken on both national and international levels.
The evolutive history of the Gallus genus, including the chicken, has been explored in many studies that have led to incompatible phylogenetic trees. The genus is made up of 4 wild fowl species: the red junglefowl (Gallus gallus, southeast Asia), the grey junglfowl (Gallus sonneratti, India), the Lafayette's junglefowl (Gallus lafayetti, Sri Lanka) and the green junglfowl (Gallus varius, Indonesia). Previous studies suggest that the ancestral branch concerns either the red junglfowl (A scenario) or the green junglfowl (B scenario). They have limits however: often only one bird per species, few genes, etc.
In a publication in the journal Genome Biology, scientists from several international teams involved with Elisabetta Giuffra of GABI (coordinator of the review), describe research priorities that are based on the progress, success and resources of the FAANG intitative (Functional Annotation of Animal Genomes) since 2015, aimed at answering current and future challenges in Animal Production.
Our Research Highlights are chosen amongst a choice selection of significant research results that were published in international scientific journals. They illustrate our main results for the year.
A catalogue of procaryote genes present in the bovine rumen has been compiled. It will help decipher the potential roles of the microbiota as a whole, in particular its ability to degrade structural carbohydrates in forages.
Where do your sea products come from? In Europe, 75% of these products are imported. It therefore seems important to guarantee a sustainable growth for aquaculture in Europe. Such is the mission of the H2020 AQUAEXCEL project, which began in 2011. Today it evolves to a third edition: AQUAEXCEL3.0.
For the first time, the characterization of incubation temperature effects of Japonese quail eggs show an impact on growth, physiology and metabolism of the birds potentially in relation with their capacity to thermoregulate.
This session is organized as part of the @BRIDGe core facilities training programs. Rendez-vous on Monday 23 November to follow the presentation by Etienne Verrier, Professor at AgroParisTech and Didier Boichard, senior scientist of the Bovine Genetics and Genomics Team.
On the contrary to mammals and birds in which sex is determined at conception by sex chromosomes (X and Y being the most well-known), it is frequent in fish and reptiles that sex be determined at least in part by water temperature at a key developmental stage.
This is true in sea bass, but, in a surprising way, the same temperature can produce males or females depending on the moment of development where they are applied. This is what a study by the Animal Genetics and Integrative Biology Unit (GABI, INRAE, AgroParisTech, Université Paris-Saclay) and the MARine Biodiversity, Exploitation and Conservation (MARBEC, IRD, Ifremer, Université de Montpellier, CNRS), found and which was published on 4 November, 2020 in the journal Ecology and Evolution.
During evolution, fish have developed a remarkable diversity of sex phenotypic control mechanisms, associating heterogametic systems such as XX/XY as in mammals or ZZ/ZW as in birds to polygenic systems or those regulated by the environment. In the rainbow trout (Oncorhynchus mykiss), sex is dictated by a simple chromosome system (XX/XY) and the major sex determinant is known (sdY gene). This genetic determinism is used to produce completely female populations (XX), which are more interesting that bisexual populations. However, male individuals are regularly observed in these XX populations.
The 2020 edition of the National Science Fair will be a virtual event due to the sanitary crisis. Scientists from INRAE in Ile-de-France are mobilized to share their work with the public. Beginning on October 2 they gave conferences, presented videos and for the public including grade-school children. The program; the earth and its inhabitants, lactic acid bacteria, urban farms, animal sciences....
A meeting is scheduled with the coordinators on September 15, at AgroParisTech Claude Bernard Center in Paris !
Check out the research studies by the Genetics of the microbiota and health Team of GABI in the INRAE press release "One Health - only one health for the Earth, animals and man".
Breast cancer is the most wide-spread cancer in the world and one of the main causes of death in women. A study implicating scientists from the Paris-Saclay University, INSERM and INRAE just established a link between night shift working and an increased risk of cancer, suggesting that disruption of circadian rythms could make tumors more agressive. This study was published in the journal Nature Communications on Wednesday, June 24, 2020.
This book provides the state of the art in terms of poultry genetics and genomics. The last similar edition was published over 10 years ago and it is now time to relate all the progress made by genomics in one edition for the poultry industry, amateur breeders, scientists and students in poultry farming along with decision-makers.
Two INRAE teams (Jouy-en-Josas) and a laboratory in Santiago, Chili, are sharing their expertise in RNA virology and molecular biology to conceive via bioinformatics a series of antisense oligonucleotides that by linking specifically to key regions of the SARS-CoV-2 viral genome, allow their destruction and therefore block viral multiplication.
Nuclear copies of mitochondrial DNA (NUMT) have already been described in several species. Dominique Rocha of the G2B team and his partners ientified and analyzed 166 bovine NUMTof a total length of 430 kpb, representing approximately 0,02% of the nuclear genome of cattle. Their studies were published in Scientific Reports.
The person hired will work with the head of the CRB-Anim infrastructure and the @BRIDGe Biological Resources Center. He/She will interact with teams contributing to CRB-Anim and with the computer scientists of the national (RARe, PNDB, IFB), or European infrastructures (EBI) implicated in the management of biological samples.
The objective of this seminar is to treat the health challenges associated with arising risks generated by climate and anthropic changes by decompartmentalizing disciplinary approaches. Experts will speak on climate, the consequences of global changes and the urgency of finding ways to act.