News

Article

14 September 2023

Redaction: GABI - Edition P. Huan

Are you a cellular biologist? INRAE is hiring a junior scientist on a research project in cellular and molecular biology!

You are a cellular biologist by training with an established experience in research, willing to contribute to the agro-ecological transition in farming by proposing an ambitious research project. Please contact the MoDiT team, Animal Models and Tissue Differentiation (www.jouy.inrae.fr/gabi). We are looking for a cellular biologist to decipher the molecular and cellular mechanisms (such as intracellular metabolism, intercellular exchanges…) that link some mutations to the appearance of developmental abnormalities.
Article

05 October 2023

Redaction: GABI - Edition P. Huan

Predicting male fertility from sperm methylome: application to 120 bulls with hundreds of artificial insemination records

Conflicting results regarding alterations to sperm DNA methylation in cases of spermatogenesis defects, male infertility and poor developmental outcomes have been reported in humans. Bulls used for artificial insemination represent a relevant model in this field, as the broad dissemination of bull semen considerably alleviates confounding factors and enables the precise assessment of male fertility. This study was therefore designed to assess the potential for sperm DNA methylation to predict bull fertility.
Article

05 October 2023

Redaction: GABI - Edition P. Huan - Translation W. Brand-Williams

Entering into the multiverse: using multiple factor analysis to characterize individualized multi-omic regulation pathways

In an article published in the journal Biostatistics, biostatisticians from the GABI unit, in partnership with oncologists and human genomicists from the University of Wisconsin-Milwaukee and the Medical College of Wisconsin, propose a new integrative approach for the quantification and characterization of the deregulation of multi-omics regulation pathways, by calculating individualized pathway disruption scores.
GABI: Animal Genetics and Integrative Biology unit
Article

14 September 2023

Redaction: M-P. Sanchez - Edition P. Huan - Translation W. Brand-Williams

A G2B team publication selected as the « Editor’s Choice » by the Editor-in-Chief of JDS

The article, "Opportunities for genomic selection of cheese-making traits in Montbéliarde cows" published in the June issue of the Journal of Dairy Science was selected by the journal's Editor-in-Chief, Paul Kononoff, as the "Editor's Choice". The article will be placed on the home page of the journal for a month and will then join the "Editor's Choice" collection.
@INRAE - Sandrine Floriot (Impact de la troncation de la protéine C-Nap1 Bovin vs Murin)
Article

05 October 2023

Redaction: GABI S. Floriot - Edition P. Huan - Translation W. Brand-Williams

C-Nap1, from the cow to the mouse, a centriolar protein gradually reveals its secrets

A study of the Caprine-like Generalized Hypoplasia Syndrome (SHGC) in the Montbeliard breed identified a mutation leading to the truncation of the C-Nap1 protein. In order to gain knowledge on the role of this protein, we created a murine model containing a similar mutation. The analysis of these mice did not confirm the role of this protein in the appearance of the SHGC syndrome but revealed its role in male fertility.
Pixabay
Article

05 October 2023

Redaction: INRAE - Edition P. Huan - Translation W. Brand-Williams

Discovering indicators of heritable resilience in laying hens

Within the context of a changing climate and the diversification of breeding methods, animals will be more exposed to disturbances of their environment. In order to identify indicators of resilience in animals to such disturbances, INRAE, Wageningen University (The Netherlands) and the selection company Hendrix Genetics (Belgium) analyzed data from more than 60 000 laying hens. They identified three easily-measured indicators for resilience which would be in part determined by genetic factors. These results, published on April 20th in Genetics Selection Evolution, lead to new perspectives for selection of more resilient laying hens.
INRAE F. Mollandin
Article

05 October 2023

Redaction: GABI - Edition P. Huan - Tranlsation W. Brand-Williams

An interview with Fanny Mollandin, a PhD student at GABI

Fanny presents her PhD subject aimed at improving sustainability and health conditions in animal production through studies on the functionnal genomes of pigs and chickens. Her PhD is financed by the H2020 GENE-SWITCH project and INRAE's Animal Genetics Division.
INRAE @Sophie Pollet
Article

05 October 2023

Redaction: INRA GABI - Edition P. Huan - Translation W. Brand-Williams

A new molecular genotyping test for selection of sports poneys breeders

Scientists from the "Integrative Biology and Equine Genetics Teams" (BIGE) at GABI have developed a 3-SNP genotyping test that explains in part, the variance of the wither size in a population of French Saddle Poneys. This new molecular genotyping test will allow the optimization of selection of reproducers and the management of reasoned couplings.
@INRAE D. Boichard
Article

05 October 2023

Redaction: GABI D. Boichard - Edition P. Huan - Translation W. Brand-Williams

Publication of dairy catlle indexes estimated with the "Single Step" method

Single Step is a genomic evaluation method that simultaneously uses all animals, whether genotyped or not, in only one step. It is a major evolution for genomic selection. This important work was done in three steps: an entirely new software was developed by INRAE (HSSGBLUP); validating studies and a comparison was done by the UMT eBIS (ASAP project); and deployment work as part of a UNIGENO project coordinated by GenEval and Idele.
Article

14 September 2023

Redaction: INRAE - Edition P. Huan

INRAE 2022 open competition: GABI is recruiting Junior Research Scientist in statistical learning and artificial intelligence

PhD (or equivalent) degree in Biostatistics / Applied Mathematics / Artificial Intelligence, with excellent training in statistical learning and data science, a strong interest in modeling biological data, as well as very good programming skills (R / Python) : Apply to become a researcher !
@ http://agriculture.gouv.fr
Article

05 October 2023

Redaction: GABI - Edtiion P. Huan - Translation W. Brand-Williams

What contribution can genetic selection make for the adaptation of agriculture to climate change?

Adapting and protecting agriculture faced with the challenges of climate change is a group reflection carried out by the Ministry of Agriculture and Food within the framework of the Varenne agricole de l'eau and adaptation to climate change. The reports and conclusions from the different working groups as well as the contribution of Animal Genetics to improve animale resilience to clmate change are available!
GABI: Animal Genetics and Integrative Biology unit
Article

14 September 2023

Redaction: GABI - Edition P. Huan

Laser microdissection allows fine in situ analysis of the interaction between extracellular bacteria and the host

Laser capture microdissection to study Bacillus cereus iron homeostasis gene expression during Galleria mellonella in vivo gut colonization.
Article

14 September 2023

Redaction: GABI - Edition P. Huan - Translation W. Brand-Williams

On our way for 2022 !

The UMR GABI wished you a beautiful and pleasant 2022. Happy new year !
@UMT eBIS
Article

05 October 2023

Redaction: GABI - Edition P. Huan - Translation W. Brand-Williams

The UMT eBIS has been labelized by the Agriculture Ministry with a renewed project

The UMT eBIS was once again labelized in 2021, joining scientists and engineers from INRAE, IDELE and ALLICE in a 5-year project to produce knowledge on the characterization of the bovine genome and genetic determinism of traits and for the develoment of selection methods and tools for this species. This UMT is hosted at the GABI laboratory at Jouy-en-Josas.
University of South Bohemia. Marc Vandeputte is the second one from the left.
Article

05 October 2023

Redaction: M. Vandeputte - Edition P. Huan

Marc Vandeputte, honoris causa Doctor of the University of South Bohemia

On 26 November, Marc Vandeputte (GABI, Genetics and Aquaculture team) was awarded an honorary doctorate by the University of South Bohemia in the Czech Republic. Johann Verreth (Professor Emeritus at the University of Wageningen) received the same distinction on the same day.
@Pixabay
Article

05 October 2023

Redaction: INRAE - Edition P. Huan - Tranlation W. Brand-Williams

Viruses of bacteria: our faithful allies against antibioresistance

Viruses are sometimes our ennemies but sometimes our friends. In the fight against pathogenic bacteria, they can be precious allies, eliminating bacteria when our medicines no longer work. But more importantly, they are not sources of new resistances to antibiotics in bacteria. This is the conclusion of a studied by scientists at INRAE, published on October 25, 2021 in the journal ISME Communications.
@INRAE Mathilde Dupont-Nivet (Truites arc-en-ciel)
Article

05 October 2023

Redaction: K. Paul & al. - Edition P. Huan - Translation W. Brand-Williams

Between positive impact and negative consequences, the complex effects of inbreeing on the reproduction of the rainbow trout

Through the genetic improvement of the rainbow trout, the efficiency of trout production over the last thirty years has increased notably. But this selection has also contributed to an increase in inbreeding, menacing genetic progress on the long term and the adaptation of populations to a changing environment. That is why scientists from the GABI unit sought to evaluate the effects of inbreeding on the reproductive performances of the rainbow trout.
@Groupe FROGS
Article

05 October 2023

Redaction: INRAE - Edition P. Huan - Translation W. Brand-Williams

FROGS : a frog attacking fungi

Microbial ecosystems (intestinal, food, soil microbiota, ....) are continuously being recognized for their major role in many fields: amongst them, fungi frequently enter scientific debates. The new version of the FROGS software allows the precise identification of fungal communities present in the microbiota in addition to the bacterial communities identified by the previous version.
@INRAE
Article

05 October 2023

Redaction: INRAE - Edition P. Huan

From the cow to poplar tree, from bees to wheat, how does genomic selection work?

For 10 years, in dairy cattle, "classical" selection has been put aside for genomic selection. This evolution has allowed more rapid progress and a considerable reduction in the cost of selection. Since then, it has been applied to an ever increasing number of animal and plant species and has spiked interest in many others.
@ Tristan Kistler
Article

05 October 2023

Redaction: T. Kistler - Edition P. Huan - Translation W. Brand-Williams

Polyandry or monoandry ?

What are the consequences on genetic evolution of an Apis melifera bee population undergoing selection?
GABI: Animal Genetics and Integrative Biology unit
Article

05 October 2023

Redaction: M. Tixier-Boichard, Edition P. Huan, translation W. Brand-Williams

The H2020 SCALA-MEDI Project Kick-off meeting was held on September 7th

The kick-off of the H2020 SCALA-MEDI project included 17 European partners for the launching of this project whose objective is the improvement of the sustainability and the quality of ovine and poultry production via the development of the adaptation potential of local breeds in the MEDIterranean area.